Physics Club endeavours to instill curiosity amongst IISTians regarding Physics. Our one and only motto is ‘Question Everything’. To that end, we have organized several sessions to shed light on various areas of physics and to instigate IISTians to probe deeper into them. We have also introduced the Physika Lecture Series. Following in the footsteps of Dr. Richard Feynman’s ‘PhysicsX’ Lecture Series, the lectures aim to bring forth the research being actively pursued by professors, to the student community.

The Quiz Club of IIST is an informal gathering of quizzing enthusiasts which meets every Friday to hold a quizzing session. The club was established in the year 2008. The club is one of the most regular clubs on campus. Teams of two take part in the quiz which is usually held by a volunteering member (or team).Teams from this club have represented the college in various intercollegiate events and have won several prizes. The club members are also responsible for organising quizzing events during the annual cultural and technical festivals and as part of swatch bharath program.

The nanosatellite club is a student driven arm of the nanosatellite program at IIST. Currently, the club is involved in mission and spacecraft design for IIST's maiden home mission "IISTnSAT" and for the flagship international collaborative missions like INSPIRE and AAREST with University of Colorado, Boulder, Caltech University, and University of Surrey.

Avionics Department's students coordinate a Computer Club for discussing computer systems related advancements. They organize training sessions, lectures, and hands-on workshops on computer systems, softwares, programming, networking, cyber security, and embedded systems. The club is currently organized by Ms. Pragya Sha, 7th Semester, B.Tech ECE (Avionics) student. Dr. B. S. Manoj is the faculty coordinator for the club. During the last one year, the club organized more than six student-driven events for the benefit of IIST students

The Movie and Performing Arts Club of IIST is an active student club which holds its sessions approximately once every two weeks on Saturday nights. These sessions usually consist of the screening of award-winning and critically acclaimed movies. This year, the club has seen an admirable increase in the staging of skits and short plays, written by the students themselves, which has popularised a healthy culture of performing arts and stagecraft in the college.

The FOSS Group, IIST is IIST's FOSS chapter aimed at promoting the use of Free and Open Source Software tools in the fields of core research pertaining to Aerospace, Avionics and the physical sciences. The group, germinating from the basic idea of a shared and thus free community, is aimed at promoting a complete or near-complete adoption of FOSS based platforms for all academic research and development activities going on at IIST. The group conducted software workshops and lectures to improve the overall comfort of students with FOSS software and scientific computing in general.

The objective of this club is to provide a platform for having open discussions on any topic in Mathematics and in connection with this; talks/lectures were arranged with a regular interval of time by Department of Mathematics.

The term Yoga is beautifully quoted as ’Skill in Action and Expression’. It is derived from the word ‘yuj’, meaning Union (Union of mind, body and spirit).